Puerto Williams to Buenos Aires

Remote and otherworldly, Antarctic is irresistible for its spectacular iceberg sculptures and calving glaciers, and for the possibility of up-close encounters with marine mammals and the iconic penguins. The Antarctic Peninsula – the main peninsula closest to South America – has a human history of almost 200 years, with explorers, sealers, whalers, and scientists who have come to work, and eventually intrepid visitors coming to enjoy this pristine and remote wilderness. It is a region of protected bays, unscaled snow-capped mountains, vast glaciers and a few places where whalers or scientists have worked. Just as irresistible are the many Gentoo and Chinstrap Penguin colonies, the seals basking on ice floes, the whales and orcas.

South Georgia is a breathtaking destination of towering snow-covered mountains, mighty glaciers, and low-lying grasslands that attract an astounding concentration of wildlife. It is possible to find Southern fur seals, Southern elephant seals and a variety of albatross species including Black-browed, Light-mantled Sooty, Grey-headed and the spectacular Wandering Albatross, plus thousands of King and Macaroni Penguins. South Georgia is also linked to the early Antarctic explorers. Captain James Cook first stepped ashore in 1775, but perhaps more famous is Ernest Shackleton’s arrival in 1916 following the sinking of his ship Endurance. Shackleton’s grave and the whaling museum at Grytviken are highlights, as would be a visit to one of the King Penguin colonies at Salisbury Plain or Gold Harbour.

Tiny Stanley, capital of the Falklands, seems in many ways like a British village fallen out of the sky. Many homes are painted in bright colours, adding visual appeal to this distant outpost. Not far offshore, the wreck of the Lady Elizabeth, is one of the many vessels remaining as a silent testimonial to the region's frequent harsh weather conditions.The islands, also known by their Spanish name of Islas Malvinas, are home to arguably more tuxedo-clad inhabitants of the penguin variety than human residents. Various species, such as Gentoo, Magellanic and the more elusive King penguins, either live here permanently or use the Falklands as a stopover on their migration route. Darwin found the islands' flora and fauna fascinating - no doubt you will, too.

Approaching from Ruta 3, it's hard to believe that the horizon line of buildings perched just beyond the windswept dunes and badlands is the most successful of all coastal Patagonia settlements. But once you get past the outskirts of town and onto the wide coastal road known as the Rambla, the picture begins to change. Ranged along the clear and tranquil Golfo Nuevo are restaurants, cafés, dive shops, and hotels, all busy—but not yet overcrowded—with tourists from around the world.Puerto Madryn is more a base for visiting nearby wildlife-watching sites like Península Valdés and Punta Tombo than a destination in its own right. The town's architecture is unremarkable, and beyond a walk along the coast there isn't much to do. Indeed, even the few museums serve mainly to introduce you to the fauna you'll see elsewhere. The exception is the beginning of whale season (May through July), when the huge animals cavort right in the bay before heading north—you can even walk out alongside them on the pier. During these months it's worth the extra expense for a room with a sea view.The many tour agencies and rental-car companies here make excursion planning easy. Aim to spend most of your time here on one- or two-day trips exploring the surroundings. Note that competition is fierce between tourism operators in destinations such as Puerto Madryn and Puerto Pirámides on Península Valdés. Take information that tour operators and even the tourism office give you about these with a grain of salt: they often exaggerate Madryn's virtues and other areas' flaws.

Glamorous and gritty, Buenos Aires is two cities in one. What makes Argentina's capital so fascinating is its dual heritage—part European, part Latin American. Plaza de Mayo resembles a grand square in Madrid, and the ornate Teatro Colón would not be out of place in Vienna. But you’ll know you’re in South America by the leather shoes for sale on cobbled streets and impromptu parades of triumphant soccer fans. Limited-production wines, juicy steaks, and ice cream in countless flavors are among the old-world imports the city has perfected.